Fournier’s gangrene is a potentially life-threatening skin infection, that affects the genital, perianal and perineal areas of the body. It can be caused by SGLT2 inhibitors used to treat diabetes.
A form of necrotizing fasciitis, Fournier’s gangrene kills soft tissues quickly, including muscle and nerves. It is caused when a skin wound allows bacteria, fungi or a virus to seep inside. According to the FDA, “Fournier’s gangrene is an extremely rare but life-threatening bacterial infection of the tissue under the skin that surrounds muscles, nerves, fat, and blood vessels of the perineum. The bacteria usually get into the body through a cut or break in the skin, where they quickly spread and destroy the tissue they infect.”